Roskilde October 21. 2021

The encapsulation retains the payload until a well-defined percentage of the BC membrane has been digested by the cellulase. When this digestion threshold has been reached there is a sudden change in permeability and the payload is fully released over a short span of time. This release pattern can be explained by a phenomenon known in materials science as percolation. New in vitro data defines narrow boundaries on the percolation threshold of the BC membrane.

The release pattern provides excellent opportunities for controlling the entestinal site of release together with opportunities for controlling the time window for release.

This substantiates that the ApiVault Technology can deliver targeted release of probiotics, prebiotics, nutraceuticals, enzymes, biologics, peptides and small molecules in predestined segments of the intestine.